Seventy-two Grownup patients have been randomly allotted to acquire either 0.02 mg/kg midazolam (Midazolam Group) or placebo (Regulate Team) as premedication prior to ESD. Sedation was accomplished by concentrating on Modified Observer’s Evaluation of Alertness/Sedation (MOAA/S) scale of three or four with continuous propofol infusion and bo